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Yoav Ben-Shlomo

Yoav Ben-Shlomo

Professor in Clinical Epidemiology

Contact Details

Research Interests

Life course epidemiology; neuroepidemiology; inequalities in health; equity of access to health services; the health of carers.

Publications

Recent Publications

Hill M, Ben-Shlomo Y. Neurological care and risk of hospital mortality for patients with Myasthenia Gravis in England. (JNNP)

Willer CJ, Sanna S, Jackson U, Scuteri A, Bonnycastle LL, Clarke R et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease . Nature Genetics 2008; 40: 161 - 169

Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen, W-M, Bonnycastle LL et al. Common variants in the GDF5-UQCC region are associated with variation in human height. Nature Genetics 2008; 40: 198 – 203.

Fish M, Bayer AJ, Gallacher JEJ, Bell T, Pickering J, Pedro S, Dunstan FD, Ben-Shlomo Y, Ebrahim S. Prevalence and Pattern of Cognitive impairment in a Community Cohort of Men in South Wales: Methodology and Findings from the Caerphilly Prospective Study. Neuroepidemiology 2008;30:25-33

Ben-Shlomo Y, Evans S, Ibrahim F, Patel B, Anson K, Chinegwundoh F, Corbishley C, Dorling D, Thomas B, Gillatt D, Kirby R, Muir G, Nargund V, Popert R, Metcalfe C, Persad R on behalf of the PROCESS study group. The risk of prostate cancer amongst Black men in the United Kingdom: The PROCESS cohort study. Eur Urology 2008;53:99-105

Vedhara K, Miles J, Crown A, McCarthy A, Shanks N, Davies D, Lightman S, Davey-Smith G, Ben-Shlomo Y. Relationship of Early Childhood Illness with Adult Cortisol in the Barry Caerphilly Growth (BCG) Cohort. Psychoneuroendocrinology 2007; 32:865-873.

Freathy RM, Weedon MN, Bennett A, Hypponen E, Relton CL, Knight B et al. Type 2 Diabetes TCF7L2 risk genotyes alter birth weight: a study of 24, 053 individuals. Am J Hum Genet 2007;80:1150-1161.

McCarthy A, Hughes R, Tilling K, Davies D, Davey Smith G, Ben-Shlomo Y. Birth weight, post-natal, infant and childhood growth and obesity in young adulthood: Evidence from the Barry Caerphilly Growth (BCG) Study. Am J Clin Nutr 2007;86:907-913.

Rasul F, Stansfeld SA, Davey Smith G, Ben Shlomo Y, Gallacher J. Psychological distress, physical illness and risk of myocardial infarction in the Caerphilly study. Psychological Medicine 2007; 37:1305-1313.

Litvan I, Halliday G, Hallett M, Goetz CG, Rocca W, Duyckaerts C et al. The etiopathogenesis of Parkinson's disease and suggestions for future research. Part I. J Neuropathol Exp Neurol 2007;66:251-277.

Frayling TM, Timpson NJ, Weedon MN et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science. 2007; 316: 889 - 894

Chinegwundoh F, Enver M, Lee A, Nargund V, Oliver T, Ben-Shlomo Y. Risk and presenting features of prostate cancer amongst African-Caribbean, South Asian and European mon in North-east London. BJU Int 2006;98:1216-1220.

Love S, Siew LK, Dawbarn D, Wilcock GK, Ben-Shlomo Y, Allen SJ. Premorbid effects of APOE on synaptic proteins in human temporal neocortex. Neurobiology of Ageing. 2006;797-803.

Lawlor DA, Martin R, Gunnell D, Galobardes B, Ebrahim S, Sandhu J, Ben-Shlomo Y, McCarron P, Davey Smith G. The association of body mass index measured in childhood, adolescence and young adulthood with coronary heart disease and stroke risk: findings from three historical cohort studies. Am J Clin Nutrition. 2006 83;767-773

Binder A, Garcia E, Wallace C, Kazeem G, Ben-Shlomo Y, Yarnell J, Sweetnam P, Brown P, Caulfield M, Skrabal F, Kotanko P, Munroe P. Haplotypes of the beta-2 adrenergic receptor associate with blood pressure in Caerphilly Prospective Study. J Hypertens 2006; 24:471-477

Plaha P, Ben-Shlomo Y, Patel NK, O'Sullivan K, Gill SS. The Caudal Zona Incerta is superior to the Subthalamic Nucleus as a target for Deep Brain Stimulation in the treatment of Parkinson's disease. Brain 2006;1732-1747

English R, Brookes ST, Avery K, Blazeby J, Ben -Shlomo Y. The effectiveness, reliability and acceptability of peer marking in first year medical students. Medical Education 2006;40:965-972.

Sandhu J, Davey Smith G, Holly J, Cole T, Ben-Shlomo Y. Timing of puberty determines serum insulin-like growth factor-I in late adulthood. J Clin Endocrinol Metab 2006;91:3150-3157.

Davies AA, Davey Smith G, May M, Ben-Shlomo Y. The association between birth weight and blood pressure is robust, amplifies with age and may be underestimated. Hypertension. 2006;48:431-436.

Lyngdoh T, Kinra S, Ben-Shlomo Y, Reddy S, Prabhakaran D, Davey Smith G, Ebrahim S on behalf of the Indian migration study group. Sib-recruitment for studying migration and its impact on obesity and diabetes. Emerging themes in Epidemiology. 2006;3:2 (1-9)

Sandhu J, Ben-Shlomo Y, Cole T, Holly J, Davey Smith G. The impact of childhood body mass index on timing of puberty, adult stature and obesity: A follow-up study based on adolescent anthropometry recorded at Christ's Hospital (1936-1964). Int J Obesity. 2006; 30:14-22.

Sandhu J, Ben-Shlomo Y , Cole T, Holly J, Davey Smith G. The impact of childhood body mass index on timing of puberty, adult stature and obesity: A follow-up study based on adolescent anthropometry recorded at Christ's Hospital (1936-1964). Int J Obesity. 2006; 30:14-22.

Wheeler B, Ben-Shlomo Y . Environmental equity, air quality, socioeconomic status and respiratory health: a linkage analysis of routine data from the Health Survey for England. J Epidemiol Comm Health. 2005;59:948-954.

Smith A, Patterson C, Yarnell J, Rumley A, Ben-Shlomo Y , Lowe G. Which haemostatic markers add to the predictive value of conventional risk factors for coronary heart disease and ischaemic stroke? The Caerphilly study. Circulation. 2005; 112:3080-3087.

Gallacher JEJ, Pickering J, Elwood PC, Bayer AJ, Yarnell JW, Ben-Shlomo Y . Glucoregulation has greater impact on cognitive performance than macro-vascular disease in men with type 2 diabetes: Data from the Caerphilly study. European Journal of Epidemiology 2005;20:761-768.

Ben-Shlomo Y . Real epidemiologists don't do ecological studies? Int J Epidemiology 2005; 34:1181-1182.

Kinnersley P, Ben-Shlomo Y , Hawthorne K, Donovan J, Chaturvedi N. The acceptability of simulated patients for studying general practice consultations. Education for Primary Care. 2005; 16:540-6

Sharp D, Ben-Shlomo Y , Beswick AD, Andrew ME, Elwood PC. Platelet aggregation in whole blood, a paradoxical predictor of ischaemic stroke: Caerphilly prospective study revisited. Platelets 2005;16:320-328.

O'Connor TG, Ben-Shlomo Y , Heron J, Golding J, Adams D, Glover V. Prenatal anxiety predicts individual differences in cortisol in pre-adolescent children. Biological Psychiatry. 2005;58:211-217.

Davey Smith G, Ben-Shlomo Y, Beswick A, Yarnell J, Lightman S, Elwood P. Cortisol, testosterone and coronary heart disease: prospective evidence from the caerphilly study. Circulation 2005;112:332-340.

Ben-Shlomo Y, Holly J, McCarthy A, Savage P, Davies D, Davey Smith G. Pre and post natal milk supplementation and adult insulin-like growth factor I: Long term follow-up of a randomised controlled trial. Cancer Epidemiology, Biomarkers and Prevention 2005;14:1336-9.

Lawlor DA, Ben-Shlomo Y , Ebrahim S, Stansfeld SA, Yarnell JWG, Gallacher JEJ, Davey Smith G. Insulin resistance is not predictive of depressive symptoms in middle-aged men: findings from the Caerphilly prospective cohort study. B r Med J 2005;330:705-706.

Nath U, Thomson R, Wood R, Ben-Shlomo Y , Lees A, Rooney C, Burn D. Population-based mortality rates and quality of death certification in Progressive Supranuclear Palsy (Steele-Richardson-Olszewski syndrome). J Neurol Neurosurgery Psychiatry 2005;76:498-502.

Martin RM, Ben-Shlomo Y , Gunnell D, Elwood P, Yarnell JWG, Davey Smith G. Breastfeeding and cardiovascular disease risk factors, incidence and mortality: the Caerphilly Study. Journal of Epidemiology and Community Health . 2005;59:121-129.

Ben-Shlomo Y , Fallon U, Sterne J, Brookes S. Do medical students without A-level mathematics have a worse understanding of the principles behind Evidence Based Medicine? Medical Teacher 2004;731-733.

Naqvi H, Ben-Shlomo Y , Baker I, Field N. Registering ischaemic heart disease: Are we meeting the targets for South Asians? J Public Health 2004; 26:365-368.

Heyderman R , Ben-Shlomo Y, Brennan CA, Somerset M. The incidence and mortality for meningococcal disease associated with area deprivation: an ecological study of hospital episode statistics for England (1991 to 1999) Archives of Diseases in Childhood 2004; 89: 1064-1068.

Lowe GDO, Sweetnam PM, Yarnell JWG, Rumley A, Bainton D, Ben-Shlomo Y . C-reactive protein, fibrin D-dimer and risk of ischaemic heart disease: combined analysis in the Caerphilly and Speedwell studies. Atherosclerosis, Thrombosis and Vascular Biology 2004;24:1957-1962.

Shaw M, Maxwell R, Rees K, Ho D, Oliver S, Ben-Shlomo Y , Ebrahim S. Gender and age inequity in the provision of coronary revascularisation in England in the 1990s: is it getting better? Social Science and Medicine 2004;59: 2499-2507.

Osaki Y, Ben-Shlomo Y , Lees AJ, Daniel SE, Colosimo C, Wenning G, Quinn N. The accuracy of clinical diagnosis of progressive supranuclear palsy. Movement Disorders 2004;19:181-189.

Sheehan J, Perry I, Reilly M, Salim A, Collins M, Twomey EM, Daly A, Loingsigh SN, Elwood P, Ben-Shlomo Y , Davy-Smith G. Q-T dispersion, Q-T maximum and risk of cardiac death in the Caerphilly Heart Study. European Journal of Cardiovascular Prevention and Rehabilitation . 2004; 11: 63-68.

Davies AA, Davey Smith G, Ben-Shlomo Y , Litchfield P. Low birthweight is associated with higher adult total cholesterol concentration in men: findings from an occupational cohort of 25,843 employees. Circulation 2004;110:1258-1262.

Fibrinogen Studies Collaboration. Collaborative meta-analysis of prospective observational studies of plasma fibrinogen and cardiovascular disease. European Journal of Cardiovascular Prevention and Rehabilitation 2004:11:9-17

Gunnell D, May M, Ben-Shlomo Y , Yarnell J, Davey Smith G. Height, leg length, and cancer: The Caerphilly Study. Nutrition and Cancer 2004;47;34-39.

Cullum A, McCarthy A, Gunnell D, Davey Smith G, Sterne JAC, Ben-Shlomo Y . Dietary restraint and the mis-reporting of anthropometric measures by middle-aged adults. Int J Obesity 2004;28:426-433.

Mitchell SMS, Hattersley AT, Knight B, Turner T, Metcalf BS, Voss LD, Davies D, McCarthy A, Wilkin TJ, Davey Smith G, Ben-Shlomo Y , Frayling TM. Lack of support for a role of the insulin gene variable number of tandem repeats minisatellite (INS-VNTR) locus in feta; growth or type 2 Diabetes-related intermediate traits in United Kingdom populations. J Clin Endocrinol Metab 2004;89:310-317.

Evan S, Ben-Shlomo Y , Persad R. Prostate cancer in Black and White men: Are there differences in risk or prognosis? BJU International 2003; 92: 878-879.

Kuh D, Ben-Shlomo Y , Lynch J, Hallqvist J. Life course epidemiology. J Epidemiol Comm Health 2003;57:778-783.

Ben-Shlomo Y , Holly J, McCarthy A, Savage P, Davies D, Gunnell D, Davey Smith G. An investigation of fetal, postnatal and childhood growth with insulin-like growth factor I and binding protein 3 in adulthood Clinical Endocrinology 2003 59:366-373.

Montgomery AA, Fahey T, Ben-Shlomo Y , Harding J. The influence of absolute cardiovascular risk, patient utilities and costs on the decision to treat hypertension: A Markov Decision Analysis. Journal of Hypertension 2003;21:1753-1759.

Fallon U, Virtamo J, Young I, McMaster D, Ben-Shlomo Y , Wood N, Whitehead AS, Davey Smith G. Homocysteine and cerebral infarction in Finnish Male smokers. Stroke 2003;34:1359-1363.

Martin RM, McCarthy A, Davey Smith G, Davies DP, Ben-Shlomo Y . Association between infant nutrition and blood pressure in early adulthood: the Barry Caerphilly Growth study. Am J Clin Nutrition 2003;1489-97.

Probert CS, Cahill DJ, McCann GL, Ben-Shlomo Y . Traditional Finals and OSCEs in predicting consultant and self-reported clinical skills of PRHOs: a pilot study. Medical Education 2003;37:597-602.

Adamson J, Ben-Shlomo Y , Chaturvedi N, Donovan J. Ethnicity and socio-economic position and gender - do they affect health care seeking behaviour? Social Science and Medicine 2003;57:895-904.

Elwood P, Pickering J, Yarnell J, O'Brien JR, Ben-Shlomo Y , Bath P. Bleeding time, stroke and myocardial infarction: the Caerphilly prospective study. Platelets 2003;14:139-141

Nath U, Ben-Shlomo Y , Thomson RG, Lees AJ, Burn DJ. Clinical Features and Natural History of Progressive Supranuclear Palsy: A Clinical Cohort Study. Neurology 2003;60:910-916.

Deane KHO, Ellis-Hill C, Jones D, Whurr R, Ben-Shlomo Y , Playford ED, Clarke CE. Systematic review of paramedical therapies for Parkinson's disease. Movement Disorders 2002; 17: 984-991.

Osaki Y, Ben-Shlomo Y , Wenning GK, Daniel SE, Hughes A, Lees AJ, Mathias CJ, Quinn N, MD. Do published criteria improve clinical diagnostic accuracy in multiple system atrophy? Neurology 2002;59:1486-1491.

Schrag A, Ben-Shlomo Y , Quinn NP. How valid is the clinical diagnosis of Parkinson's disease in the community? J Neurol Neurosurg Psychiatry 2002;73:529-534

Schrag A, Ben-Shlomo Y , Quinn N. How common are complications of Parkinson's disease? J Neurol 2002;249:419-423.

Kis B, Schrag A, Ben-Shlomo Y , Klein C, Gasperi A, Spoegler F, Schoenhuber R, Pramstaller PP. Novel three -stage ascertainment method: Prevalence of Parkinson's Disease and parkinsonism and Parkinson's Disease in South Tyrol, Italy. Neurology 2002;58:1820-1825.

Frayling T, Hattersley A, McCarthy A, Holly J, Mitchell S, Gloyn AL, Davies D, Davey Smith G & Ben-Shlomo Y . A putative functional polymorphism in the IGF-I gene: Association studies with type 2 diabetes, adult height, glucose tolerance and fetal growth in UK populations. Diabetes 2002;51:2313-2316.

Castelon Konkiewitz E,. Trender-Gerhard I, Kamm C, Warner T, Ben-Shlomo Y . Gasser T, Conrad B, Ceballos-Baumann AO. Service-based survey of dystonia in Munich. Neuroepidemiology 2002;21:202-206.

Camfield LA, Ben-Shlomo Y , Warner TT for the Epidemiological Study of Dystonia in Europe (ESDE) Collaborative Group. Impact of cervical dystonia on quality of life. Mov Disorders 2002:17; 834-838.

Ben-Shlomo Y , Camfield L, Warner T. on behalf of the ESDE collaborative group. What are the determinants of quality of life in people with cervical dystonia? J Neurol Neurosurg Psychiatry 2002; 72: 608-614.

May M. McCarron P. Stansfeld S. Ben-Shlomo Y. Gallacher J. Yarnell J. Davey Smith G. Elwood P. Ebrahim S. Does psychological distress predict the risk of ischemic stroke and transient ischemic attack? the Caerphilly study. Stroke 2002; 33:7-12.

Ben-Shlomo Y , Kuh D. A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives. Int J Epidemiol 2002;31: 285-293.

Ebrahim S, May M, Ben-Shlomo Y , McCarron P, Frankel S, Davey Smith G, Yarnell J. Sexual intercourse and risk of ischaemic stroke and coronary heart disease: the Caerphilly study J Epidemiol Community Health 2002;56:99-102.

Hughes AJ, Daniel SE, Ben-Shlomo Y , Lees AJ. The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service. Brain 2002;125:861-870.

Lees AJ, Katzenschlager R, Head J, Ben-Shlomo Y , on behalf of the Parkinson´s Disease Research Group of the United Kingdom. Ten-year follow-up of three different initial treatments in de-novo PD: a randomised trial. Neurology 2001;57:1687-1694.

Nath U, Ben-Shlomo Y , Thomson RG, Morris HR, Wood NW, Lees AJ, Burn DJ. The Prevalence of Progressive Supranuclear Palsy (Steele-Richardson-Olszewski syndrome) in the United Kingdom. Brain 2001;124:1438-1449. [Co-director of research and major co-author]

Greenwood R, McCarron P, Elwood P, Ben-Shlomo Y , Bayer A, Baker I, Frankel S, Ebrahim S, Murray L, Davey Smith G. The incidence and aetiology of stroke in the Caerphilly and Speedwell Collaborative Studies I: Methods and incidence of events. Public Health 2001;115:4-11.

McCarron P, Greenwood R, Elwood P, Ben-Shlomo Y , Bayer A, Baker I, Frankel S, Ebrahim S, Murray L, Davey Smith G. The incidence and aetiology of stroke in the Caerphilly and Speedwell Collaborative Studies II: Risk factors for ischaemic stroke. Public Health 2001;115:12-20.

Fallon U, Ben-Shlomo Y , Elwood P, Ubbink JB, Davey Smith G. Homocysteine and coronary heart disease in the Caerphilly cohort: a 10 year follow up. Heart 2001; 85:153-158.

Fallon U, Elwood P, Ben-Shlomo Y , Ubbink JB, Greenwood R, Davey Smith G. Homocysteine and stroke: results from the Caerphilly study. J Epidemiol Community Health 2001; 55: 91-96.

The Epidemiological Study of Dystonia in Europe (ESDE) Collaborative Group . A prevalence study of primary dystonia in eight European countries. J Neurol 2000;247:787-792.

Florey CV, Ben-Shlomo Y , Egger M. Epidemiology and the World Wide Web: Is there a "Net" benefit? Epidemiologic Reviews 2000; 22: 181-185.

Schrag A, Ben-Shlomo Y, Quinn N. Cross-sectional prevalence survey of idiopathic Parkinsons disease and parkinsonism in London. British Medical Journal 2000;321:21-2.

Montgomery AA, Ben-Shlomo Y, McCarthy A, Davies D, Elwood P, Davey Smith G. Birth size and arterial compliance in a cohort of young adults. Lancet 2000;355;2136-2137.

Wenning GK, Ben-Shlomo Y, Hughes A, Daniel SE, Lees A, Quinn NP. What features are most useful to distinguish definite multiple system atrophy from Parkinson's disease? J Neurol Neurosurg Psychiatry 2000;68 434-440.

The Epidemiological Study of Dystonia in Europe (ESDE) Collaborative Group. Sex-related influences on the frequency and age of onset of primary dystonia. Neurology 1999;53:1871.

Tanner CM.  Ben-Shlomo Y. Epidemiology of Parkinson's disease. Advances in Neurology 1999;80:153-9.

Schrag A, Ben-Shlomo Y, Quinn NP. The population prevalence of progressive supranuclear palsy and multiple system atrophy. Lancet 1999;354:171-175

Ben-Shlomo Y, Davey Smith G. Commentary: Socioeconomic position should be measured accurately. British Medical Journal 1999;318:844-845.

McNally S, Ben-Shlomo Y, Newman S. The effects of respite care on informal carers' well-being: a systematic review. Disability and Rehabilitation 1999;21:1-14.

Schrag A, Ben-Shlomo Y, Brown R, Quinn N. Young onset Parkinson's disease revisited - clinical features, natural history and mortality. Movement Disorders 1998;13:885-894.

Dong W, Ben-Shlomo Y, Colhoun H, Chaturvedi N. Gender differences in accessing cardiac surgery across England: a cross-sectional analysis of the Health Survey for England. Soc Sci Med 1998;47:1773-1780.

Ben-Shlomo Y, Churchyard A, Head J, Hurwitz B, Overstall P, Ockelford J, and Andrew Lees on behalf of the Parkinsons Disease Research Group of the United Kingdom. Investigation by Parkinsons Disease Research Group of United Kingdom into excess mortality seen with combined levodopa and selegiline treatment in patients with early, mild Parkinsons disease: further results of randomised trial and confidential inquiry. British Medical Journal 1998;316:1191-1195.

Kuh D, Ben-Shlomo Y (eds). A life course approach to chronic disease epidemiology: tracing the origins of ill-health from early to adult life. Oxford Medical Publications 1997 Oxford.